GDC-0927 (SRN-927) (Synonyms: SRN-927) |
Catalog No.GC32920 |
GDC-0927 (SRN-927) (SRN-927) est un antagoniste sélectif des récepteurs aux œstrogènes puissant, non stéroÏdien, biodisponible par voie orale.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1642297-01-5
Sample solution is provided at 25 µL, 10mM.
GDC-0927 (SRN-927) is a novel, potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist.
GDC-0927 is a novel, potent, non-steroidal, orally bioavailable, selective ER antagonist/ER degrader (SERD) that induces tumor regression in estrogen receptor (ER)+breast cancer (BC) patient-derived xenograft models[1].
[1]. MN Dickler, et al. Abstract PD5-10: A first-in-human phase I study to evaluate the oral selective estrogen receptor degrader (SERD), GDC-0927, in postmenopausal women with estrogen receptor positive (ER+) HER2-negative metastatic breast cancer (BC). AACR; Cancer Res 2018;78(4 Suppl):Abstract nr PD5-10.
Average Rating: 5
(Based on Reviews and 19 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *