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Gemcitabine-O-Si(di-iso)-O-Mc

Catalog No.GC60870

Gemcitabine-O-Si(di-iso)-O-Mc est un conjugué médicament-lieur pour l'ADC avec une puissante activité antitumorale en utilisant la Gemcitabine (un antimétabolite analogue de nucléoside pyrimidique et un agent antinéoplasique;), lié via le lieur ADC.

Products are for research use only. Not for human use. We do not sell to patients.

Gemcitabine-O-Si(di-iso)-O-Mc Chemical Structure

Taille Prix Stock Qté
1mg
510,00 $US
En stock
5mg
908,00 $US
En stock
10mg
1 391,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Gemcitabine-O-Si(di-iso)-O-Mc is a drug-linker conjugate for ADC with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent;), linked via the ADC linker[1].

Antibody drug conjugates (ADC) couple therapeutic monoclonal antibodies (mAb) with potent toxins through a linker that is stable within systemic circulation, but cleaves within the target cells[1].

[1]. Mathew C. Finniss, et al. A versatile acid-labile linker for antibody-drug conjugate. MedChemComm, Issue 9, 2014.

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Review for Gemcitabine-O-Si(di-iso)-O-Mc

Average Rating: 5 ★★★★★ (Based on Reviews and 21 reference(s) in Google Scholar.)

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