GSK-1482160 |
Catalog No.GC63838 |
GSK-1482160 est un modulateur allostérique négatif disponible par voie orale du récepteur P2X7.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1001389-72-5
Sample solution is provided at 25 µL, 10mM.
GSK-1482160 is an orally available negative allosteric modulator of the P2X7 receptor. P2X7 receptors are involved in the production of pro-inflammatory cytokines, such as Il-1β, by central and peripheral immune cells. GSK-1482160 has the potential for the research of inflammation diseases[1].
[1]. Ali Z, et al. Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects. Br J Clin Pharmacol. 2013;75(1):197-207. doi:10.1111/j.1365-2125.2012.04320.x
Average Rating: 5
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