GSK-1482160 |
| Catalog No.GC63838 |
GSK-1482160 is an orally available negative allosteric modulator of the P2X7 receptor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1001389-72-5
Sample solution is provided at 25 µL, 10mM.
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GSK-1482160 is an orally available negative allosteric modulator of the P2X7 receptor. P2X7 receptors are involved in the production of pro-inflammatory cytokines, such as Il-1β, by central and peripheral immune cells. GSK-1482160 has the potential for the research of inflammation diseases[1].
[1]. Ali Z, et al. Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects. Br J Clin Pharmacol. 2013;75(1):197-207. doi:10.1111/j.1365-2125.2012.04320.x
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