HPI 1 |
| Catalog No.GC11045 |
HPI 1 est un puissant antagoniste du GLI avec une valeur IC50 de 1,1 μM. HPI 1 montre une activité anti-proliférative. HPI 1 diminue l'expression de l'ARNm de GLI1. HPI 1 inhibe la formation de colonies de manière dose-dépendante.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 599150-20-6
Sample solution is provided at 25 µL, 10mM.
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Hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4 and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced activation). Also inhibits Hh pathway activation
Review for HPI 1
Average Rating: 5 (Based on Reviews and 4 reference(s) in Google Scholar.)
Review for HPI 1
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