Imanixil |
Catalog No.GC39390 |
Imanixil (base libre HOE-402) est un inducteur du récepteur LDL (LDLR).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 75689-93-9
Sample solution is provided at 25 µL, 10mM.
Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and consequently attenuates atherosclerosis development[1].
[1]. Draijer R, et al. HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice. Biochem Pharmacol. 2002 May 1;63(9):1755-61.
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