IU1-248 |
| Catalog No.GC63027 |
IU1-248, un dérivé de IU1, est un inhibiteur puissant et sélectif de l'USP14 avec une IC50 de 0,83μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2307472-03-1
Sample solution is provided at 25 µL, 10mM.
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IU1-248, a derivative of IU1, is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM.
IU1-248 exhibits an IC50 value of 0.83 μM toward USP14, which is comparable to that of IU1-47 (IC50=0.68 μM) and 10-fold more potent than that of IU1 (IC50=12.25 μM)[1].
[1]. Yiwei Wang, et al. Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res. 2018 Dec;28(12):1186-1194.
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