JZP-430 |
| Catalog No.GC34640 |
JZP-430 est un inhibiteur puissant, hautement sélectif et irréversible du domaine 6 de l'α/β-hydrolase (ABHD6) avec une IC50 de 44 nM, présente une sélectivité d'environ 230 fois par rapport À l'hydrolase d'amide d'acide gras (FAAH) et À la lipase acide lysosomale (LAL ).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1672691-74-5
Sample solution is provided at 25 µL, 10mM.
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JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL)[1]. IC50: 44 nM (ABHD6, human)[1]
[1]. Patel JZ, et al. Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. ChemMedChem. 2015 Feb;10(2):253-65.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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