KDdiA-PC |
Catalog No.GC43997 |
KDdiA-PC est une sorte de LDL oxydée (oxLDL) et est un ligand pour le récepteur CD36 des macrophages.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 439904-34-4
Sample solution is provided at 25 µL, 10mM.
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as phosphatidylcholine species containing a fragmented, oxidized short-chain fatty acid remnant at the sn-2 position. KDdiA-PC is one of the most potent CD36 ligands among the oxLDL species. KDdiA-PC confers CD-36 scavenger receptor binding affinity to LDL at a frequency of only two to three KDdiA-PC molecules/LDL particle, and may be one of the more important structural determinants of oxLDL.
Average Rating: 5
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