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MRT-14

Catalog No.GC64419

MRT-14 est un puissant antagoniste de Smo. Smo est le composant majeur impliqué dans la transduction du signal des morphogènes Hedgehog (Hh). MRT-14 a le potentiel pour la recherche de plusieurs types de cancers liés À une signalisation Hh anormale.

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MRT-14 Chemical Structure

Cas No.: 1263131-83-4

Taille Prix Stock Qté
5 mg
90,00 $US
En stock
10 mg
144,00 $US
En stock
50 mg
423,00 $US
En stock
100 mg
675,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

MRT-14 is a potent antagonist of Smo. Smo is the major component involved in signal transduction of the Hedgehog (Hh) morphogens. MRT-14 has the potential for the research of several types of cancers linked to abnormal Hh signaling[1].

[1]. Manetti F, et al. Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists. Mol Pharmacol. 2010;78(4):658-665.

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