N-Desmethyl Galanthamine (Synonyms: N-demethylgalanthamine, Norgalantamine, Norgalanthamine) |
| Catalog No.GC61116 |
La N-desméthyl galanthamine est un métabolite de la galanthamine.
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Cas No.: 41303-74-6
Sample solution is provided at 25 µL, 10mM.
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N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2].
[1]. Bachus R, et al. The O-demethylation of the antidementia drug galanthamine is catalysed by cytochrome P450 2D6. Pharmacogenetics. 1999;9(6):661-668. [2]. Melanie-Jayne R. Howes, et al. Acetylcholinesterase inhibitors of natural origin. International Journal of Research in Pharmaceutical and Biomedical Sciences 3(SI 1):67-86.
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