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NecroIr1

Catalog No.GC69543

NecroIr1 est un complexe d'iridium (III) qui induit la nécrose des cellules résistantes au cisplatine dans le cancer du poumon (A549R). NecroIr1 s'accumule sélectivement dans les mitochondries, entraînant un stress oxydatif et une perte de potentiel membranaire mitochondrial (MMP). NecroIr1 peut activer la kinase RIPK3 et la pseudokinase MLKL impliquées dans l'interaction récepteur-récepteur, régulant ainsi l'expression de CDK4.

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NecroIr1 Chemical Structure

Taille Prix Stock Qté
5mg
405,00 $US
En stock
10mg
720,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

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