[Nle4,D-Phe7]-α-MSH (trifluoroacetate salt) |
| Catalog No.GC41745 |
[Nle4,D-Phe7]-α-MSH is a synthetic analog of α-melanocyte stimulating hormone (α-MSH).
Products are for research use only. Not for human use. We do not sell to patients.
![[Nle4,D-Phe7]-α-MSH (trifluoroacetate salt) Chemical Structure](/media/struct/GC4/GC41745.png "[Nle4,D-Phe7]-α-MSH (trifluoroacetate salt) Chemical Structure")
Sample solution is provided at 25 µL, 10mM.
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[Nle4,D-Phe7]-α-MSH is a synthetic analog of α-melanocyte stimulating hormone (α-MSH). It is 26-fold more potent than α-MSH at inducing adenylate cyclase activity in mouse melanoma cells in vitro. [Nle4,D-Phe7]-α-MSH also induces tyrosinase activity in a time-dependent manner in mouse melanoma cells. In vivo, [Nle4,D-Phe7]-α-MSH (1.8 μg/g) induces long-term skin darkening in R. pipiens (frogs). Formulations containing [Nle4,D-Phe7]-α-MSH have been used to induce melanogenesis in patients with erythropoietic protoporphyria.
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