Oleic Acid ethyl ester (Synonyms: Ethyl Oleate) |
| Catalog No.GC40733 |
L'oléate d'éthyle est un ester d'acide gras formé par la condensation de l'acide oléique et de l'éthanol.
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Cas No.: 111-62-6
Sample solution is provided at 25 µL, 10mM.
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Oleic acid is a monounsaturated fatty acid and is one of the major components of membrane phospholipids. It contributes about 17% of the total fatty acids esterified to phosphatidylcholine in porcine platelets. Oleic acid ethyl ester is a neutral, more lipid-soluble form of oleic acid. As the free acid, it inhibits collagen-stimulated platelet aggregation by approximately 90% at a concentration of 10 µg/ml. It inhibits fMLF-induced neutrophil aggregation and degranulation by 55% and 68%, respectively, at 5 µM. Oleic acid, whether applied extracellularly (EC50 = ~60 µM) to human platelets or released from membrane phospholipids, causes an increase in intracellular calcium levels.
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