Orelabrutinib |
| Catalog No.GC39634 |
L'orélabrutinib (ICP-022) est un inhibiteur puissant, actif par voie orale et irréversible de la tyrosine kinase de Bruton (BTK) avec une activité antinéoplasique potentielle. L'orélabrutinib empêche À la fois l'activation de la voie de signalisation du récepteur de l'antigène des cellules B (BCR) et l'activation médiée par la BTK des voies de survie en aval, inhibant la croissance des cellules B malignes qui surexpriment la BTK.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1655504-04-3
Sample solution is provided at 25 µL, 10mM.
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Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor. Orelabrutinib has the potential for B-cell malignancies treatment[1].
[1]. Wei Xu, et al. Safety, Tolerability and Efficacy of Orelabrutinib, Once a Day, to Treat Chinese Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Cell Leukemia. Blood (2019) 134 (Supplement_1): 4319.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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