PEG3-C4-OBn |
| Catalog No.GC39316 |
PEG3-C4-OBn est un lieur PROTAC À base de polyéthylène glycol (PEG). Le PEG3-C4-OBn peut être utilisé dans la synthèse du dégradeur PROTAC SGK3-1. PROTAC SGK3 degrader-1 est un puissant dégradeur SKG3 basé sur PROTAC.
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Cas No.: 2381196-79-6
Sample solution is provided at 25 µL, 10mM.
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1. PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC[1][2].
[1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 5. [2]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.
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