Pentaacetylquercetin (Synonyms: NSC 115919, Peracetylated Quercetin, Quercetin Pentaacetate) |
| Catalog No.GC40189 |
La pentaacétylquercétine pourrait interagir avec la protéine F avec une énergie de liaison plus faible et une meilleure stabilité pour bloquer l'adhésion virale.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1064-06-8
Sample solution is provided at 25 µL, 10mM.
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Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively).
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