Phentolamine Mesylate |
Catalog No.GC16291 |
Le mésylate de phentolamine (méthanesulfonate de phentolamine) est un bloqueur réversible, non sélectif et actif par voie orale des récepteurs adrénergiques α1 et α2 qui dilate les vaisseaux sanguins pour réduire la résistance vasculaire périphérique.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 65-28-1
Sample solution is provided at 25 µL, 10mM.
Phentolamine mesylate is a competitive, reversible α-adrenoceptor antagonist with an IC50 between 5 and 30 nM.
References:
[1]. Giussani, D.A., et al., Alpha 1- and alpha 2-adrenoreceptor actions of phentolamine and prazosin on breathing movements in fetal sheep in utero. J Physiol, 1995. 486 ( Pt 1): p. 249-55.
[2]. Saeed, M., et al., Alpha-adrenoceptor blockade by phentolamine causes beta-adrenergic vasodilation by increased catecholamine release due to presynaptic alpha-blockade. J Cardiovasc Pharmacol, 1982. 4(1): p. 44-52.
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