PIM inhibitor 1 phosphate (Synonyms: INCB053914 phosphate) |
| Catalog No.GC19419 |
Le phosphate d'Uzansertib (INCB053914) est un inhibiteur de pan-PIM kinase compétitif pour l'ATP, actif par voie orale, avec des IC50 de 0,24 nM, 30 nM, 0,12 nM pour PIM1, PIM2, PIM3, respectivement. L'inhibiteur de PIM 1 phosphate a une large activité anti-proliférative contre une variété de lignées cellulaires tumorales hématologiques.
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Cas No.: 2088852-47-3
Sample solution is provided at 25 µL, 10mM.
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PAK4-IN-1 is an inhibitor of Pim extracted from patent WO 2017044730 A1, compound 1; has an IC50 of less than 35 nM.
[1]. WO 2017044730 A1
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