Propargyl-PEG4-alcohol |
| Catalog No.GC60305 |
Le propargyl-PEG4-alcool est un lieur PROTAC À base de PEG qui peut être utilisé dans la synthèse des PROTAC.
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Cas No.: 87450-10-0
Sample solution is provided at 25 µL, 10mM.
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Propargyl-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.
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