Prostaglandin E2-1-glyceryl ester (Synonyms: PGE21glyceryl ester) |
Catalog No.GC44718 |
2-Arachidonoyl glycerol has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.
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Cas No.: 37497-47-5
Sample solution is provided at 25 µL, 10mM.
2-Arachidonoyl glycerol has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in prostaglandin glycerol ester formation. The biosynthesis of PGH, PGD, PGE, PGF, and Thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of these prostaglandin products has been investigated, little is known about their intrinsic biological activity.
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