(rac)-PF-998425 |
| Catalog No.GC63292 |
(Rac)-PF-998425 est un antagoniste puissant, sélectif et non stéroÏdien des récepteurs aux androgènes (AR).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1076225-26-7
Sample solution is provided at 25 µL, 10mM.
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(rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].
[1]. Li JJ, et al. Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008;51(21):7010-7014.
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