Rheb inhibitor NR1 |
| Catalog No.GC39292 |
L'inhibiteur de Rheb NR1 est un inhibiteur de Rheb avec une IC50 de 2,1μM dans le test Rheb-IVK.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2216763-38-9
Sample solution is provided at 25 µL, 10mM.
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Rheb inhibitor NR1 is a Rheb inhibitor with an IC50 of 2.1 µM in the Rheb-IVK assay. Rheb inhibitor NR1 also is a selective mTORC1 inhibitor. NR1 inhibits the phosphorylation of T389pS6K1 and increases the phosphorylation of S473pAKT in a dose-dependent manner[1].
[1]. Mahoney SJ, et al. A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. Nat Commun. 2018 Feb 7;9(1):548.
Average Rating: 5 (Based on Reviews and 39 reference(s) in Google Scholar.)
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