Sartorypyrone B |
| Catalog No.GC46217 |
La Sartorypyrone B est un analogue 2β-acétoxyle de la chevalone C. La Sartorypyrone B est obtenue À partir de l'extrait d'acétate d'éthyle de la culture du champignon marin associé aux éponges Neosartorya tsunodae (KUFC 9213). La Sartorypyrone B présente une forte activité inhibitrice de croissance, avec des IG50 de 17,8, 20,5 et 25,0 μM, respectivement, pour MCF-7, NCI-H460 et A375-C5. Sartorypyrone B a le potentiel pour la recherche sur l'adénocarcinome du sein, le cancer du poumon non À petites cellules et les mélanomes.
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Cas No.: 1452396-11-0
Sample solution is provided at 25 µL, 10mM.
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Sartorypyrone B is a fungal metabolite that has been found in N. fischeri and has anticancer activity.1 It inhibits the growth of MCF-7, H460, and A375 cancer cells (GI50s = 17.8, 20.5, and 25 μM, respectively).
|1. Eamvijarn, A., Gomes, N.M., Dethoup, T., et al. Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213). Tetrahedron 69(40), 8583-8591 (2013).
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