Sartorypyrone B |
Catalog No.GC46217
One-Click Copy Product Info
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La Sartorypyrone B est un analogue 2β-acétoxyle de la chevalone C. La Sartorypyrone B est obtenue À partir de l'extrait d'acétate d'éthyle de la culture du champignon marin associé aux éponges Neosartorya tsunodae (KUFC 9213). La Sartorypyrone B présente une forte activité inhibitrice de croissance, avec des IG50 de 17,8, 20,5 et 25,0 μM, respectivement, pour MCF-7, NCI-H460 et A375-C5. Sartorypyrone B a le potentiel pour la recherche sur l'adénocarcinome du sein, le cancer du poumon non À petites cellules et les mélanomes.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1452396-11-0
Sample solution is provided at 25 µL, 10mM.
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Sartorypyrone B is a fungal metabolite that has been found in N. fischeri and has anticancer activity.1 It inhibits the growth of MCF-7, H460, and A375 cancer cells (GI50s = 17.8, 20.5, and 25 μM, respectively).
|1. Eamvijarn, A., Gomes, N.M., Dethoup, T., et al. Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213). Tetrahedron 69(40), 8583-8591 (2013).
| Cas No. | 1452396-11-0 | SDF | |
| Canonical SMILES | CC(OC1=C2C[C@]3([H])[C@@](CC[C@@]4([H])[C@@]3(C)CC[C@]5([H])[C@]4(C)C[C@H](OC(C)=O)[C@H](OC(C)=O)C5(C)C)(C)O1)=CC2=O | ||
| Formula | C30H42O7 | M.Wt | 514.7 |
| Solubility | Soluble in DMSO | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 1.9429 mL | 9.7144 mL | 19.4288 mL |
| 5 mM | 388.6 μL | 1.9429 mL | 3.8858 mL |
| 10 mM | 194.3 μL | 971.4 μL | 1.9429 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >95.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)