Sparfosic acid trisodium |
| Catalog No.GC39643 |
L'acide sparfosique trisodique est un antimétabolite de l'ADN et un puissant inhibiteur de l'aspartate transcarbamoyl transférase.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 70962-66-2
Sample solution is provided at 25 µL, 10mM.
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Sparfosic acid trisodium, is a potent inhibitor of aspartate transcarbamoyl transferase, with anti-tumor and antimetabolite activity. Aspartate transcarbamoyl transferase catalyzes the second step of de novo pyrimidine biosynthesis[1][2].
[1]. Wang J, et al. Elevated cyclin A associated kinase activity promotes sensitivity of metastatic human cancer cells to DNA antimetabolite drug. Int J Oncol. 2015 Aug;47(2):782-90. [2]. Angela D. Morris, et al. A New, Efficient, Two Step Procedure for the Preparation of the Antineoplastic Agent Sparfosic Acid
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