SR 13800 |
| Catalog No.GC50163 |
Le SR 13800 est un puissant inhibiteur du transporteur de monocarboxylate 1 (MCT1). Le SR 13800 a une activité anticancéreuse.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 227321-12-2
Sample solution is provided at 25 µL, 10mM.
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Potent MCT1 inhibitor (IC50 = 0.5 nM); blocks proliferation of Raji lymphoma cells in vitro. Also inhibits lactate uptake in breast cancer cells in vitro.
Murray et al (2005) Monocarboxylate transporter MCT1 is a target for immunosuppression. Nat.Chem.Biol. 1 371 PMID:16370372 |Wang et al (2014) Synthesis and structure-activity relationships of pteridine dione and trione monocarboxylate transporter 1 inhibitors. J.Med.Chem. 57 7317 PMID:25068893
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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