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Tenidap (Synonyms: CP 66,248)

Catalog No.GC11853

Tenidap, un anti-inflammatoire non stéroÏdien, est un inhibiteur sélectif de la COX-1, avec des valeurs IC50 de 0,03 μM et 1,2 μM pour la COX-1 et la COX-2, respectivement.

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Tenidap Chemical Structure

Cas No.: 120210-48-2

Taille Prix Stock Qté
1mg
44,00 $US
En stock
5mg
97,00 $US
En stock
10mg
171,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC50 values of 0.03 µM and 1.2 µM for COX-1 and COX-2, respectively. Tenidap has anti-inflammatory and antirheumatic properties[1][2]. Tenidap is also a specific SLC26A3 inhibitor.

References:
[1]. Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation. J Pharmacol Exp Ther. 1997 Aug;282(2):1094-101.
[2]. Blackburn WD Jr, et al. Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone. Arthritis Rheum. 1995 Oct;38(10):1447-56.

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Average Rating: 5 ★★★★★ (Based on Reviews and 28 reference(s) in Google Scholar.)

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