Vamorolone |
| Catalog No.GC39564 |
La vamorolone (VBP15) est un anti-inflammatoire stéroÏdien dissociatif actif par voie orale et un stabilisateur de membrane de première classe.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 13209-41-1
Sample solution is provided at 25 µL, 10mM.
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Vamorolone (VBP15) is a first-in-class, orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone shows potent NF-κB inhibition and substantially reduces hormonal effects[1][2].
[1]. Heier CR, et al. VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects. EMBO Mol Med. 2013 Oct;5(10):1569-85. [2]. Dillingham BC, et al. VBP15, a novel anti-inflammatory, is effective at reducing the severity of murine experimental autoimmune encephalomyelitis. Cell Mol Neurobiol. 2015 Apr;35(3):377-387. [3]. Heier CR, et al. Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy. Life Sci Alliance. 2019 Feb 11;2(1). pii: e201800186.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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