YH-306 |
| Catalog No.GC64992 |
YH-306 est un agent antitumoral. YH-306 supprime la croissance tumorale colorectale et les métastases via la voie FAK. YH-306 inhibe de manière significative la migration et l'invasion des cellules cancéreuses colorectales. YH-306 supprime puissamment la prolifération non inhibée et induit l'apoptose cellulaire. YH-306 supprime l'activation de FAK, c-Src, paxilline et PI3K, Rac1 et l'expression de MMP2 et MMP9. YH-306 inhibe également la polymérisation de l'actine médiée par le complexe de protéine liée À l'actine (Arp2/3).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1373764-75-0
Sample solution is provided at 25 µL, 10mM.
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YH-306 is an antitumor agent. YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. YH-306 significantly inhibits the migration and invasion of colorectal cancer cells. YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis. YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9. YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization[1].
[1]. Dai F, et al. A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. J Cell Mol Med. 2015 Feb;19(2):383-95.
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