Signaling Pathways

Ac-ETDK(myr)-AMC acetate is a DLAT-derived ε-N-myristoyllysine peptide substrate for fatty-acid deacylase HDAC11, used in fluorescence-based HDAC11 activity assays.

Acetyl-pepstatin ammonium is an aspartic protease ( PRs ) inhibitor that targets HIV-1 protease and XMRV protease with K i values of 13 nM and 712 nM, respectively.

APP669-711 acetate is an N-terminally extended amyloid β peptide ( Aβ (-3)-40) that forms amyloid fibrils and co-deposits with Aβ in brain plaques, and also serves as a plasma biomarker for assessing brain Aβ load.

Bethanidine hydriodide is an orally active antihypertensive agent and adrenergic neuron blocker.

CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG trisodium solution (100 mM ± 3 mM) is a monomeric raw material that can be used for nucleic acid synthesis.

CPTH2 -d 4 is the deuterated-labeled CPTH2.

Ciprofloxacin hydrochloride (Bay-09867 hydrochloride) is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent.

Histone H3 (1-25), amide acetate is a synthetic N-terminal tail peptide derived from histone H3, which can be used to identify substrates of histone methyltransferases (HMTs).

Imlunestrant -d 4 (LY-3484356-d 4 ) is the deuterated-labeled Imlunestrant.

NCP26 TFA is an ATP-competitive ProRS inhibitor (with a K D of 271 nM in the absence of proline, and a K D of 0.35 nM in the presence of 100 μM proline).

OSU-2S TFA is a non-immunosuppressive derivative of Fingolimod hydrochloride (FTY720).

PROTAC CARM1 degrader-1 TFA is a highly selective CARM1 PROTAC degrader, with a DC 50 of 8.1 nM in MCF‑7 cells.

(R)-AR/BRD4 RIPTAC-1 is the R-enantiomer of AR/BRD4 RIPTAC-1.

(R)-Vanzacaftor -d 4 ((R)-VX-121-d 4 ) is the deuterated-labeled (R)-Vanzacaftor.

(S)-Phenylpiracetam ((S)-Carphedon; (S)-Fonturacetam; (S)-MRZ 9547) is an orally active and selective dopamine transporter inhibitor, with K i = 56 μM.

Temozolomide - 15 N (NSC 362856- 15 N) is the 15 N-labeled Temozolomide.

Tri-GalNAc-NH2 is a synthetic tri-N-acetylgalactosamine ligand that targets the asialoglycoprotein receptor (ASGPR).

Vevorisertib tetrahydrochloride (ARQ 751 tetrahydrochloride) is an orally active allosteric AKT inhibitor that blocks AKT phosphorylation.

Rfamide TFA (Arginylphenylalaninamide TFA) is a neuropeptide that has contraction-inducing activity in gastropod muscles.

Adamantan-2-amine (2-Aminoadamantane) serves as the hydrophobic tag structural unit of Tubulin degrader 2 and is used for the synthesis of anticancer drugs that target tubulin via a dual mechanism.

RB 101 hydrochloride is a blood-brain barrier-crossing prodrug as well as aminopeptidase N and neutral endopeptidase-24.11 inhibitor.

HaloAUTAC tt15 is an autophagy-targeting chimera (AUTAC), that targets the Halo Tag carrying proteins, and degrades via the autophagy mechanism.

LLC355 is a discoidin domain receptor 1 ( DDR1 ) ATTEC degrader with a DC 50 of 150.8 nM.

CP61 acetate is a CtBP1 and CtBP2 inhibitor that binds to dimeric CtBP1 and allosterically inhibits NADH binding, disrupting the NADH -dependent dimerization of CtBP1 and CtBP2, inducing aberrant mitosis and micronucleus formation, thereby inhibiting cell proliferation and colony formation.