TVB-3664 |
Catalog No.GC19976 |
TVB-3664 es un inhibidor de la sintasa de Ácidos grasos (FASN) disponible por vÍa oral, reversible, potente, selectivo y altamente biodisponible, con valores IC50 de 18 nM y 12 nM para la sÍntesis de palmitato de células humanas y de ratÓn, respectivamente. TVB-3664 reduce significativamente la palmitoilaciÓn de tubulina y la expresiÓn de ARNm.
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Cas No.: 2097262-58-1
Sample solution is provided at 25 µL, 10mM.
TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression[1][2].
Average Rating: 5
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