TVB-3664 |
Catalog No.GC19976 |
TVB-3664 est un inhibiteur de synthase d'acide gras (FASN) disponible par voie orale, réversible, puissant, sélectif et hautement biodisponible, avec des valeurs IC50 de 18 nM et 12 nM pour la synthèse de palmitate de cellules humaines et de souris, respectivement. TVB-3664 réduit significativement la palmitoylation de la tubuline et l'expression de l'ARNm.
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Cas No.: 2097262-58-1
Sample solution is provided at 25 µL, 10mM.
TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression[1][2].
Average Rating: 5
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