TVB-3664 |
| Catalog No.GC19976 |
TVB-3664는 인간 및 마우스 세포 팔미테이트 합성에 대한 IC50 값이 각각 18nM 및 12nM인 경구 이용 가능, 가역적, 강력하고 선택적이고 생체 이용률이 높은 지방산 합성 효소(FASN) 억제제입니다. TVB-3664는 튜불린 팔미토일화 및 mRNA 발현을 유의하게 감소시킵니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2097262-58-1
Sample solution is provided at 25 µL, 10mM.
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TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression[1][2].
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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