TVB-3664 |
| カタログ番号GC19976 |
TVB-3664 は経口投与可能な、可逆的、強力、選択的、生体利用性の高い脂肪酸シンターゼ (FASN) 阻害剤であり、ヒトおよびマウス細胞のパルミチン酸合成に対する IC50 値はそれぞれ 18 nM および 12 nM です。 TVB-3664 は、チューブリンのパルミトイル化と mRNA 発現を大幅に減少させます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2097262-58-1
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression[1][2].
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *