E3 ligase Ligand 10 |
Catalog No.GC35924 |
E3 ligase Ligand 10 es un ligando para E3 ubiquitina ligasa. El ligando 10 de ligasa E3 se puede conectar al ligando para proteÍna mediante un conector para formar PROTAC. Los PROTAC son inductores de la degradaciÓn mediada por ubiquitinaciÓn de proteÍnas promotoras del cÁncer.
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Cas No.: 1073560-68-5
Sample solution is provided at 25 µL, 10mM.
E3 ligase Ligand 10 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 10 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
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