E3 ligase Ligand 10 |
| Catalog No.GC35924 |
E3 리가아제 리간드 10은 E3 유비퀴틴 리가아제에 대한 리간드입니다. E3 리가제 리간드 10은 링커에 의해 단백질에 대한 리간드에 연결되어 PROTAC를 형성할 수 있습니다. PROTAC은 암 촉진 단백질의 유비퀴틴화 매개 분해를 유도합니다.
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Cas No.: 1073560-68-5
Sample solution is provided at 25 µL, 10mM.
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E3 ligase Ligand 10 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 10 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
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