Inicio>>Nε-(1-Carboxymethyl)-L-lysine

Nε-(1-Carboxymethyl)-L-lysine (Synonyms: CML)

Catalog No.GC41513

Nε-(1-Carboxymethyl)-L-lysine (CML) is an advanced glycation end product (AGE), produced by the oxidative modification of glycated proteins during oxidative stress.

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Nε-(1-Carboxymethyl)-L-lysine Chemical Structure

Cas No.: 5746/4/3

Tamaño Precio Disponibilidad Cantidad
1mg
69,00 $
Disponible
5mg
171,00 $
Disponible
10mg
253,00 $
Disponible
25mg
599,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Nε-(1-Carboxymethyl)-L-lysine (CML) is an advanced glycation end product (AGE), produced by the oxidative modification of glycated proteins during oxidative stress. Levels of CML increase with aging and during diabetes, cancer, vascular disease, and other pathologies marked by oxidative stress. CML activates the membrane-bound receptor for AGEs (RAGE), triggering signaling through MAPKs and NF-κB, whereas truncation of RAGE produces a soluble protein that binds CML and reduces signaling.

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