NecroIr2 |
| Catalog No.GC69544 |
NecroIr2 es un compuesto de iridio (III) que induce la necrosis en células resistentes al cisplatino (A549R) en cáncer de pulmón. NecroIr2 se acumula selectivamente en las mitocondrias, lo que causa estrés oxidativo y pérdida del potencial de membrana mitocondrial (MMP). NecroIr2 puede activar la quinasa serina-treonina receptora interactiva con RIPK3 y el dominio similar a quinasa pseudocinasa mixta MLKL, regulando la expresión de CDK4.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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