Olutasidenib (FT-2102) (Synonyms: FT-2102) |
Catalog No.GC31874 |
Olutasidenib (FT-2102) (FT-2102) es un inhibidor selectivo y penetrante del cerebro altamente potente, activo por vÍa oral, de la isocitrato deshidrogenasa 1 mutante (IDH1), con valores IC50 de 21,2 nM y 114 nM para IDH1-R132H e IDH1-R132C , respectivamente .
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1887014-12-1
Sample solution is provided at 25 µL, 10mM.
Olutasidenib is a highly potent, selective inhibitor of mutant Isocitrate dehydrogenase (IDH)1 that could be used in the treatment of acute myeloid leukemia.
[1]. JM Watts, et al. A phase 1 dose escalation study of the IDH1m inhibitor, FT-2102, in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
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