LSD1-IN-6 |
| رقم الكتالوجGC36485 |
LSD1-IN-6 (المركب 4 م) هو مثبط قوي وقابل للانعكاس من ديميثيلاز 1 الخاص بالليسين (LSD1) ، مع IC50 يبلغ 123 نانومتريزيد LSD1-IN-6 Lys4 ثنائي الميثيل من هيستون H3 ، ولا يظهر أي تأثير على التعبير عن LSD1
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Cas No.: 2035912-43-5
Sample solution is provided at 25 µL, 10mM.
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LSD1-IN-6 (Compound 4m) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1]. IC50: 123 nM (LSD1)[1]
[1]. Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.
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