GDC-6036 |
| رقم الكتالوجGC64510 |
GDC-6036 (المركب 17 أ) هو مثبط قوي لـ K-Ras G12C مع IC50 أقل من 0.01 ميكرومتريحتوي GDC-6036 على EC50 من 2 نانومتر في خلايا K-Ras G12C- الألكلة HCC1171
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Cas No.: 2417987-45-0
Sample solution is provided at 25 µL, 10mM.
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GDC-6036 (compound 17a) is a potent K-Ras G12C inhibitor with an IC50 of <0.01 μM. GDC-6036 has an EC50 of 2 nM in K-Ras G12C-alkylation HCC1171 cells[1].
[1]. Sushant Malhotra, et al. Fused ring compounds. WO2020097537A2.
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