GPCR/G protein
Research Areas
- Neuropeptide FF/AF Receptors(51)
- Neuropeptide S Receptor(3)
- GPBA Receptor(3)
- Trace Amine 1 Receptor(2)
- GPCR protein(1)
- FFAR3(1)
- Formyl Peptide Receptors(11)
- 5-HT Receptor(414)
- Acetylcholine(28)
- Adenosine Deaminase(10)
- Adenosine Receptor(138)
- Adenosine Kinase(5)
- Adiponectin Receptor(3)
- Adrenergic Receptor(431)
- Adrenergic Transporters(5)
- Apelin Receptor(9)
- Angiotensin Receptor(117)
- Bombesin Receptors(23)
- Bradykinin Receptors(29)
- Calcitonin and Related Receptors(10)
- Cannabinoid Receptor(111)
- Calcimimetic Agent(2)
- CaSR(25)
- CCK1 Receptors(7)
- CCK2 Receptors(7)
- CCR(95)
- Chemokine Receptors(23)
- CRF1 Receptors(10)
- CRF2 Receptors(3)
- CXCR(93)
- CysLT1 receptor(1)
- Endothelin Receptor(53)
- EP1 Receptor(2)
- EP4 Receptor(2)
- ERRγ(1)
- ETA Receptors(5)
- ETB Receptors(5)
- Free Fatty Acid Receptors(16)
- Galanin Receptors(11)
- Ghrelin Receptors(11)
- GHSR(20)
- GIP Receptor(5)
- Glucagon Receptor(54)
- Glucocorticoid Receptor(94)
- GLUT1(1)
- Gonadotropin-Releasing Hormone Receptors(3)
- GPCR19(12)
- GPR109A(4)
- GPR119(10)
- GPR120(9)
- GPR35(10)
- GPR44(1)
- GPR55(11)
- Hydroxycarboxylic Acid Receptors(5)
- Leukotriene Receptor(57)
- LPA Receptor(12)
- LPL Receptor(62)
- LTD4 Receptor(1)
- mGluR (123)
- Melanin-concentrating Hormone Receptors(7)
- Melanocortin (MC) Receptors(57)
- Melatonin Receptors(23)
- Motilin Receptor(7)
- MT Receptor(1)
- Non-selective CRF(7)
- Neurotensin Receptors(26)
- NK2 Receptors(7)
- NK3 Receptor(5)
- NOP Receptor(20)
- NPY Receptors(26)
- Orexin(3)
- Orphan 7-TM Receptors(6)
- OX Receptor(52)
- Oxytocin Receptors(22)
- P2Y Receptor(65)
- PACAP Receptors(7)
- PAF Receptors(7)
- Peptide Receptors(14)
- PGD2 Receptor(1)
- Prostaglandin Receptor(174)
- Prostanoid Receptors(25)
- Protease-Activated Receptors(9)
- RGS(2)
- S1P receptor(8)
- Secretin Receptors(1)
- Sensory Neuron-Specific Receptors(1)
- Somatostatin Receptor(43)
- Sigma Receptor(59)
- Vasopressin Receptor(34)
- 17,20-lyase(4)
- Ras(163)
- Urotensin-II Receptor(10)
- VIP Receptors(6)
- EBI2/GPR183(7)
- TSH Receptor(10)
- NK Receptor(1)
- GPR81(1)
- C3aR(1)
- CysLT2 receptor(1)
- S1P receptor inhibitor(22)
- CCKB(1)
- FFAR1 (GPR40)(20)
- GPR84(10)
- Neuromedin U Receptors(2)
- Kisspeptin Receptor(6)
- CRFR(27)
- RGS Protein(5)
- Urotensin Receptor(7)
- Cholecystokinin Receptor(28)
- GPR139(4)
- mAChR(191)
- MCHR1 (GPR24)(16)
- Neurokinin Receptor(76)
- cGMP(27)
- GRK(3)
- GPR88(1)
- Amylin Receptor(3)
- Arrestin(8)
- Mas-related G-protein-coupled Receptor (MRGPR)(6)
- GCGR(7)
- GLP Receptor(16)
- Succinate Receptor 1(1)
- PTHR(2)
- Protease Activated Receptor (PAR)(6)
- Free Fatty Acid Receptor(5)
- Formyl Peptide Receptor (FPR)(3)
- Hydroxycarboxylic Acid Receptor (HCAR)(2)
- RXFP Receptor(2)
- Adhesion G Protein-coupled Receptors (AGPCRs)(1)
- Taste Receptor(1)
- GPR52(1)
Products Related to GPCR/G protein(3538)
- GC79231RMC-4998 TFAPurity: >99.00%
RMC-4998 TFA is an orally active inhibitor targeting the active or GTP-bound state of the KRAS G12C mutant.
- GC79232PAR2 modulator-1CAS: 2378159-28-3Purity: >98.50%
PAR2 modulator-1 is a biased protease-activated receptor 2 ( PAR2 ) inhibitor.
- GC79234NRAS-G4-ligand-1CAS: 1185061-66-8Purity: >90.00%
NRAS-G4-ligand-1 is a NRAS-G4 binder with K d values of 0.25 μM (AlexaFluor 647-labeled) and 0.932 μM (biotinylated), respectively.
- GC79235IACS-56676CAS: 3105153-34-9Purity: >98%
IACS-56676 is a selective NRAS G12D inhibitor with a target IC 50 of 0.031 μM.
- GC79236(1R)-KRAS inhibitor-24CAS: 3030576-46-3Purity: >98.00%
(1R)-KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC 50 of < 100 nM for KRas G12V, KRas WT and KRas G12R [1] .
- GC79237(R)-KRAS G12D inhibitor 28 hydrochloride dihydrateCAS: 3081520-70-6Purity: >99.50%
Zecdarasib hydrochloride dihydrate is a Kirsten rat sarcoma virus oncogene homolog ( KRAS ) inhibitor with antitumor activity.
- GC79238(4R)-BBO-8520CAS: 2893809-52-2Purity: >98.00%
(4R)-BBO-8520 (Compound 314), an isomer of BBO-8520, is a selective KRAS G12C inhibitor.
- GC79245KRAS G12D-IN-30CAS: 3022287-75-5Purity: >99.00%
KRAS G12D-IN-30 (Compound 4) is a KRAS inhibitor.
- GC79248MrgprX2 antagonist-9CAS: 3095296-92-4Purity: >99.50%
MrgprX2 antagonist-9 is an MRGPRX2 antagonist with an IC 50 of 0.1-100 nM.
- GC79249MrgprX2 antagonist-11CAS: 3116847-13-0Purity: >99.00%
MrgprX2 antagonist-11 is a potent MrgprX2 antagonist.
- GC79250MrgprX2 antagonist-10CAS: 3116848-78-0Purity: >98.50%
MrgprX2 antagonist-10 is a potent MRGPRX2 antagonist.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC79229 | NZ-107 | 107186-52-7 | >99.00% | |
NZ-107 is an orally active leukotriene receptor antagonist. | ||||
| GC79230 | BBO-11818 | 3029443-36-2 | >99.50% | |
BBO-11818 is an orally active, highly selective (relative to NRAS and HRAS ), non-covalent pan- KRAS inhibitor ( IC 50 =28-120 nM). | ||||
| GC79231 | RMC-4998 TFA | - | >99.00% | |
RMC-4998 TFA is an orally active inhibitor targeting the active or GTP-bound state of the KRAS G12C mutant. | ||||
| GC79232 | PAR2 modulator-1 | 2378159-28-3 | >98.50% | |
PAR2 modulator-1 is a biased protease-activated receptor 2 ( PAR2 ) inhibitor. | ||||
| GC79233 | SR-1815 | 2636710-78-4 | >98% | |
SR-1815 is a small molecule multi-kinase inhibitor. | ||||
| GC79234 | NRAS-G4-ligand-1 | 1185061-66-8 | >90.00% | |
NRAS-G4-ligand-1 is a NRAS-G4 binder with K d values of 0.25 μM (AlexaFluor 647-labeled) and 0.932 μM (biotinylated), respectively. | ||||
| GC79235 | IACS-56676 | 3105153-34-9 | >98% | |
IACS-56676 is a selective NRAS G12D inhibitor with a target IC 50 of 0.031 μM. | ||||
| GC79236 | (1R)-KRAS inhibitor-24 | 3030576-46-3 | >98.00% | |
(1R)-KRAS inhibitor-24 (compound 115c) is a pyridopyrimidine KRAS inhibitor, with an IC 50 of < 100 nM for KRas G12V, KRas WT and KRas G12R [1] . | ||||
| GC79237 | (R)-KRAS G12D inhibitor 28 hydrochloride dihydrate | 3081520-70-6 | >99.50% | |
Zecdarasib hydrochloride dihydrate is a Kirsten rat sarcoma virus oncogene homolog ( KRAS ) inhibitor with antitumor activity. | ||||
| GC79238 | (4R)-BBO-8520 | 2893809-52-2 | >98.00% | |
(4R)-BBO-8520 (Compound 314), an isomer of BBO-8520, is a selective KRAS G12C inhibitor. | ||||
| GC79239 | RAS-IN-5 | 3061844-70-7 | >98% | |
RAS-IN-5 (Example 2) is a RAS inhibitor. | ||||
| GC79240 | RM-046 | 3058972-05-4 | >98% | |
RM-046 is an orally active, selective ternary complex inhibitor of KRAS Q61H (active form). | ||||
| GC79241 | SHY-867 | 2446484-96-2 | >99.50% | |
SHY-867 is a pan RAS inhibitor. | ||||
| GC79242 | SHY-855 | 2446485-15-8 | >98.50% | |
SHY-855 is a pan RAS inhibitor. | ||||
| GC79243 | RNK08954 | 3032602-44-8 | >98% | |
RNK08954 is an orally active KRAS G12D inhibitor with a K d of 0.0395 nM. | ||||
| GC79244 | Eras-4001 | 3024878-19-8 | >98.00% | |
Eras-4001 is a potent, orally active pan- KRAS inhibitor with K d values of 110, 13 and 39 pM against wild-type, G12D and G12V mutant KRAS, respectively, and exhibits selectivity toward wild-type HRAS and NRAS. | ||||
| GC79245 | KRAS G12D-IN-30 | 3022287-75-5 | >99.00% | |
KRAS G12D-IN-30 (Compound 4) is a KRAS inhibitor. | ||||
| GC79246 | RMC-9945 | 2922732-38-3 | >98.00% | |
RMC-9945 (RM-044) is a selective, covalent, and orally active RAS (ON) G12D inhibitor. | ||||
| GC79247 | HEP-50768 | 3036387-75-1 | >99.00% | |
HEP-50768 is an orally active and selective MRGPRX4 ( hX4 ) antagonist. | ||||
| GC79248 | MrgprX2 antagonist-9 | 3095296-92-4 | >99.50% | |
MrgprX2 antagonist-9 is an MRGPRX2 antagonist with an IC 50 of 0.1-100 nM. | ||||
| GC79249 | MrgprX2 antagonist-11 | 3116847-13-0 | >99.00% | |
MrgprX2 antagonist-11 is a potent MrgprX2 antagonist. | ||||
| GC79250 | MrgprX2 antagonist-10 | 3116848-78-0 | >98.50% | |
MrgprX2 antagonist-10 is a potent MRGPRX2 antagonist. | ||||
| GC79251 | PBF-999 | 1620909-95-6 | >98.50% | |
PBF-999 is a phosphodiesterase10A (PDE-10A) and adenosine A2A receptor (A2AR) dual antagonist. | ||||
| GC79252 | Amanozine | 537-17-7 | >98.00% | |
Amanozine (Compound 15) is a 5-HT 3 serotonin receptor agonist. | ||||