GPCR/G protein

Research Areas

Products Related to GPCR/G protein(3538)

GC79277 Solaprubart
CAS: 3057433-10-7
Purity: >99.50%
Solaprubart (STAR-0310) is a fully human IgG1 subtype monoclonal antibody targeting OX40 (CD134/TNFRSF4), with a K d of 7.2 nM.
GC79278 Vedastotug
CAS: 2878367-20-3
Purity: >99.50%
Vedastotug is a human monoclonal antibody targeting TNFRSF4/OX40/CD134, with its corresponding isotype control being Human IgG1 kappa, Isotype Control [1] .
GC79282 CTR/AMYR modulator-1
CAS: 3097482-67-9
Purity: >99.50%
CTR/AMYR modulator-1 is a calcitonin receptor/amylin receptor modulator.
GC79283 CCKBR agonist-2
CAS: 923714-61-8
Purity: >99.50%
CCKBR agonist-2 (Compound z-44) is a Gi-preferring CCKBR agonist.
GC79288 Mazapertine
CAS: 134208-17-6
Purity: >99.00%
Mazapertine is an orally active antipsychotic agent.
GC79292 PG-901
CAS: 322639-20-3
Purity: >99.00%
PG-901 is a full, selective MC5R agonist ( EC 50 = 0.072 nM for hMC5R).
GC79293 PIPE-791
CAS: 2901868-37-7
Purity: >98%
PIPE-791 is an orally active, blood-brain barrier-permeable selective antagonist of LPAR1.
GC79294 Betovumeline hydrochloride
CAS: 1364078-75-0
Purity: >99.50%
Betovumeline hydrochloride is the agonist for muscarinic receptor and can be used for researchs of neurological disorders [1] .
GC79295 4-Piperidyl N-(2-biphenyl)carbamate
CAS: 171722-92-2
Purity: >99.50%
4-Piperidyl N-(2-biphenyl)carbamate (compound MA) is a competitive muscarinic acetylcholine receptor ( mAChR ) antagonist.
GC79296 Direclidine citrate
CAS: 3028447-14-2
Purity: >98.50%
Direclidine (NBI-1117568, HTL-0016878) citrate is a selective orthosteric agonist targeting the muscarinic acetylcholine M4 receptor, exhibiting very low affinity for M1, M2, M3, and M5 receptors.
GC79297 HTL-9936
CAS: 1438242-59-1
Purity: >98%
HTL-9936 is an orally active partial agonist of muscarinic M1 receptor.
GC79298 PRAME peptide (425-433) acetate
Purity: >98.00%
PRAME peptide (425-433) acetate is a proteasome-degraded peptide derived from the cancer-testis antigen PRAME (Preferentially Expressed Antigen in Melanoma ).
GC79299 Modimelanotide acetate
Purity: >98.00%
Modimelanotide (ABT-719) acetate is an α-melanocyte-stimulating hormone analog.
GC79300 XAT-14
CAS: 3107904-59-3
Purity: >98.50%
XAT-14 is a Furanocoumarin derivative.
GC79301 GS-5759
CAS: 1346653-91-5
Purity: >99.00%
GS-5759 is both a β₂-adrenergic receptor agonist and a PDE4 inhibitor.
GC79302 CCKBR agonist-1
CAS: 2923120-30-1
Purity: >98.00%
CCKBR agonist-1 (Compound 3r1) is a Gq-protein-preferring cholecystokinin B receptor ( CCKBR ) agonist with an EC 50 of 35 pM.
GC79303 VU0477573
CAS: 1946021-40-4
Purity: >98.00%
VU0477573 is a brain-penetrant partial negative allosteric modulator of metabotropic glutamate receptor subtype 5 ( mGluR5 ).
GC79304 VU6066098
CAS: 3055537-47-5
Purity: >98%
VU6066098 is a blood-brain barrier penetrant, orally active inhibitor of metabotropic glutamate receptor subtype 2 ( mGlu2 ), with IC 50 values of 77 nM and 111 nM against human and rat targets, respectively.
GC79305 MPPG TFA
Purity: >99.50%
MPPG TFA, phenylglycine analogue, is a potent and selective metabotropic glutamate receptor ( mGluR ) antagonist with a k D value of 9.2 μM.
GC79306 VU6053371
Purity: >98%
VU6053371 (BI03738809) is a first-in-class (FIC), selective, orally active, and brain-penetrant metabotropic glutamate receptor subtype 3 ( mGlu3 ) positive allosteric modulator (PAM) with EC 50 s of 103 nM and 112 nM for human and rat mGlu3.
GC79307 NNC0165-1273 acetate
Purity: >99.50%
NNC0165-1273 acetate is a selective NPY Y2 receptor agonist with a K i of 2 nM and an EC 50 of 5.0 nM.
GC79308 Fmoc-DL-Leu-OH
CAS: 126727-03-5
Purity: >99.50%
Fmoc-DL-Leu-OH acts as a partial agonist of the neurotensin NTS1 receptor ( NTS1R ) with an EC 50 of 215.50 μM.
GC79309 NTRC-739
CAS: 1612188-96-1
Purity: >99.00%
NTRC-739 is a selective nonpeptide partial neurotensin receptor type 2 (NTS2) agonist with an EC 50 of 12 nM and a K i of 153 nM.
GC79310 PD-149163
CAS: 169528-11-4
Purity: >99.50%
PD-149163 is an NTR-1 agonist.

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC79277	Solaprubart	3057433-10-7	>99.50%
GC79277	Solaprubart (STAR-0310) is a fully human IgG1 subtype monoclonal antibody targeting OX40 (CD134/TNFRSF4), with a K d of 7.2 nM.
GC79278	Vedastotug	2878367-20-3	>99.50%
GC79278	Vedastotug is a human monoclonal antibody targeting TNFRSF4/OX40/CD134, with its corresponding isotype control being Human IgG1 kappa, Isotype Control [1] .
GC79282	CTR/AMYR modulator-1	3097482-67-9	>99.50%
GC79282	CTR/AMYR modulator-1 is a calcitonin receptor/amylin receptor modulator.
GC79283	CCKBR agonist-2	923714-61-8	>99.50%
GC79283	CCKBR agonist-2 (Compound z-44) is a Gi-preferring CCKBR agonist.
GC79288	Mazapertine	134208-17-6	>99.00%
GC79288	Mazapertine is an orally active antipsychotic agent.
GC79292	PG-901	322639-20-3	>99.00%
GC79292	PG-901 is a full, selective MC5R agonist ( EC 50 = 0.072 nM for hMC5R).
GC79293	PIPE-791	2901868-37-7	>98%
GC79293	PIPE-791 is an orally active, blood-brain barrier-permeable selective antagonist of LPAR1.
GC79294	Betovumeline hydrochloride	1364078-75-0	>99.50%
GC79294	Betovumeline hydrochloride is the agonist for muscarinic receptor and can be used for researchs of neurological disorders [1] .
GC79295	4-Piperidyl N-(2-biphenyl)carbamate	171722-92-2	>99.50%
GC79295	4-Piperidyl N-(2-biphenyl)carbamate (compound MA) is a competitive muscarinic acetylcholine receptor ( mAChR ) antagonist.
GC79296	Direclidine citrate	3028447-14-2	>98.50%
GC79296	Direclidine (NBI-1117568, HTL-0016878) citrate is a selective orthosteric agonist targeting the muscarinic acetylcholine M4 receptor, exhibiting very low affinity for M1, M2, M3, and M5 receptors.
GC79297	HTL-9936	1438242-59-1	>98%
GC79297	HTL-9936 is an orally active partial agonist of muscarinic M1 receptor.
GC79298	PRAME peptide (425-433) acetate	-	>98.00%
GC79298	PRAME peptide (425-433) acetate is a proteasome-degraded peptide derived from the cancer-testis antigen PRAME (Preferentially Expressed Antigen in Melanoma ).
GC79299	Modimelanotide acetate	-	>98.00%
GC79299	Modimelanotide (ABT-719) acetate is an α-melanocyte-stimulating hormone analog.
GC79300	XAT-14	3107904-59-3	>98.50%
GC79300	XAT-14 is a Furanocoumarin derivative.
GC79301	GS-5759	1346653-91-5	>99.00%
GC79301	GS-5759 is both a β₂-adrenergic receptor agonist and a PDE4 inhibitor.
GC79302	CCKBR agonist-1	2923120-30-1	>98.00%
GC79302	CCKBR agonist-1 (Compound 3r1) is a Gq-protein-preferring cholecystokinin B receptor ( CCKBR ) agonist with an EC 50 of 35 pM.
GC79303	VU0477573	1946021-40-4	>98.00%
GC79303	VU0477573 is a brain-penetrant partial negative allosteric modulator of metabotropic glutamate receptor subtype 5 ( mGluR5 ).
GC79304	VU6066098	3055537-47-5	>98%
GC79304	VU6066098 is a blood-brain barrier penetrant, orally active inhibitor of metabotropic glutamate receptor subtype 2 ( mGlu2 ), with IC 50 values of 77 nM and 111 nM against human and rat targets, respectively.
GC79305	MPPG TFA	-	>99.50%
GC79305	MPPG TFA, phenylglycine analogue, is a potent and selective metabotropic glutamate receptor ( mGluR ) antagonist with a k D value of 9.2 μM.
GC79306	VU6053371	-	>98%
GC79306	VU6053371 (BI03738809) is a first-in-class (FIC), selective, orally active, and brain-penetrant metabotropic glutamate receptor subtype 3 ( mGlu3 ) positive allosteric modulator (PAM) with EC 50 s of 103 nM and 112 nM for human and rat mGlu3.
GC79307	NNC0165-1273 acetate	-	>99.50%
GC79307	NNC0165-1273 acetate is a selective NPY Y2 receptor agonist with a K i of 2 nM and an EC 50 of 5.0 nM.
GC79308	Fmoc-DL-Leu-OH	126727-03-5	>99.50%
GC79308	Fmoc-DL-Leu-OH acts as a partial agonist of the neurotensin NTS1 receptor ( NTS1R ) with an EC 50 of 215.50 μM.
GC79309	NTRC-739	1612188-96-1	>99.00%
GC79309	NTRC-739 is a selective nonpeptide partial neurotensin receptor type 2 (NTS2) agonist with an EC 50 of 12 nM and a K i of 153 nM.
GC79310	PD-149163	169528-11-4	>99.50%
GC79310	PD-149163 is an NTR-1 agonist.