GPCR/G protein

Research Areas

Products Related to GPCR/G protein(3732)

GC84053 Schisantherin D
CAS: 64917-82-4
Purity: >99.50%
Schisantherin D is a lignan.
GC84062 Semaglutide- 13 C 6 , 15 N TFA
Purity: >96.00%
Semaglutide- 13 C 6, 15 N TFA is the 13 C- and 15 N-labeled Semaglutide TFA.
GC84068 Setmelanotide monoacetate
CAS: 2759937-80-7
Purity: >99.50%
Setmelanotide monoacetate (RM-493 monoacetate) is a blood-brain barrier-permeable, selective MC4R agonist with a K i value of 2.1 nM for hMC4R.
GC84094 SLW131
CAS: 681511-84-2
Purity: >99.50%
SLW131 is a CCR7 antagonist with a K i value of 9.85 nM.
GC84111 VUBI1
CAS: 2245237-53-8
Purity: >98.00%
VUBI1 ( SOS1 activator 1) is a benzimidazole derivative and SOS1 activator with a K d of 44 nM.
GC84112 SOS1-IN-12
CAS: 2654741-56-5
Purity: >98.00%
SOS1-IN-12 is a potent son of sevenless homolog 1 ( SOS1 ) inhibitor with a K i of 0.11 nM for SOS1 and an IC 50 of 47 nM for pERK.
GC84113 Sosimerasib
CAS: 2839563-01-6
Purity: >98.50%
Sosimerasib is an orally active KRAS G12C inhibitor.
GC84148 Surinabant
CAS: 288104-79-0
Purity: >98.00%
Surinabant (SR 147778) is an orally active, selective cannabinoid receptor type 1 CB1R antagonist.
GC84206 Tetrahydrocortisol-d 5
Purity: >99.00%
Tetrahydrocortisol-d 5 is the deuterium labeled Tetrahydrocortisol.
GC84256 Tilisolol hydrochloride
CAS: 62774-96-3
Purity: >99.50%
Tilisolol hydrochloride (N-696) is a non-selective β-adrenergic antagonist with vasodilatory and hypotensive activities.
GC84306 Trihexyphenidyl-d 5 hydrochloride
Purity: >99.50%
Trihexyphenidyl-d 5 hydrochloride is deuterium labeled Trihexyphenidyl hydrochloride.
GC84320 TRV045
CAS: 2256030-24-5
Purity: >98.00%
TRV045 is a selective Sphingosine-1-phosphate subtype 1 receptor agonist with no effect on lymphocyte transport.
GC84330 TUG-2181
CAS: 2653994-24-0
Purity: >98.00%
TUG-2181 is an antagonist of GPR84 with an IC 50 value of 34 nM.
GC84344 UKH-1114
CAS: 2113664-14-3
Purity: >99.50%
UKH-1114 is a selective TMEM97 (a sigma-2 receptor) agonist with a K i values of 1279 and 46 nM for σ1R and σ2R/ TMEM97, respectively.
GC84373 Vasorelaxant agent-2
CAS: 53242-88-9
Vasorelaxant agent-2 (Compound 8h) targets α1A-adrenergic receptor with an affinity of pD2=5.4.
GC84394 VU0467319
CAS: 1432438-14-6
Purity: >98.50%
VU0467319 (Compound VU319) is a highly selective and blood-brain-permeable, orally active M1 positive allosteric modulator (PAM) ( EC 50: 492 nM).
GC84395 VU6043653
CAS: 3032791-06-0
Purity: >99.50%
VU6043653 is a potent, selective and cross the blood-brain barrier metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC 50 value of 325 nM for h mGlu5 [1] .
GC84396 VVD-699
CAS: 3055319-82-6
Purity: >99.50%
VVD-699 is a covalent blocker of the RAS-p110α interaction with oral activity.
GC84417 Xanomeline-d 3
CAS: 175615-28-8
Purity: >99.00%
Xanomeline-d 3 (LY-246708-d 3 ) is deuterium labeled Xanomeline.
GC84432 YM-31636 free base
CAS: 159081-22-8
Purity: >98.50%
YM-31636 free base is an orally active, potent and selective 5-HT 3 receptor agonist with a K i value of 0.2 nM.
GC84433 YNT-185
CAS: 1804978-81-1
Purity: >98.00%
YNT-185 is a nonpeptide, selective orexin type-2 receptor (OX2R) agonist, with EC 50 s of 0.028 and 2.75 μM for OX2R and OX1R, respectively.
GC84435 YT 146
CAS: 90596-75-1
Purity: >99.50%
YT 146 is a potent agonist of A2 adenosine receptor (A2 AR) agonist.
GC84441 Z-3578
CAS: 473687-20-6
Purity: >99.50%
Z-3578 is an orally active small-molecule antagonist of MrgX2 with potent antipseudoallergic activity, exhibiting a K D value of 729 nM.
GC84447 ZCL279
CAS: 664975-73-9
Purity: >99.00%
ZCL279 is a small molecule modulator (SMM) that inhibits Cdc42-intersectin (ITSN) interaction.

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC84053	Schisantherin D	64917-82-4	>99.50%
GC84053	Schisantherin D is a lignan.
GC84062	Semaglutide- 13 C 6 , 15 N TFA	-	>96.00%
GC84062	Semaglutide- 13 C 6, 15 N TFA is the 13 C- and 15 N-labeled Semaglutide TFA.
GC84068	Setmelanotide monoacetate	2759937-80-7	>99.50%
GC84068	Setmelanotide monoacetate (RM-493 monoacetate) is a blood-brain barrier-permeable, selective MC4R agonist with a K i value of 2.1 nM for hMC4R.
GC84094	SLW131	681511-84-2	>99.50%
GC84094	SLW131 is a CCR7 antagonist with a K i value of 9.85 nM.
GC84111	VUBI1	2245237-53-8	>98.00%
GC84111	VUBI1 ( SOS1 activator 1) is a benzimidazole derivative and SOS1 activator with a K d of 44 nM.
GC84112	SOS1-IN-12	2654741-56-5	>98.00%
GC84112	SOS1-IN-12 is a potent son of sevenless homolog 1 ( SOS1 ) inhibitor with a K i of 0.11 nM for SOS1 and an IC 50 of 47 nM for pERK.
GC84113	Sosimerasib	2839563-01-6	>98.50%
GC84113	Sosimerasib is an orally active KRAS G12C inhibitor.
GC84148	Surinabant	288104-79-0	>98.00%
GC84148	Surinabant (SR 147778) is an orally active, selective cannabinoid receptor type 1 CB1R antagonist.
GC84206	Tetrahydrocortisol-d 5	-	>99.00%
GC84206	Tetrahydrocortisol-d 5 is the deuterium labeled Tetrahydrocortisol.
GC84256	Tilisolol hydrochloride	62774-96-3	>99.50%
GC84256	Tilisolol hydrochloride (N-696) is a non-selective β-adrenergic antagonist with vasodilatory and hypotensive activities.
GC84306	Trihexyphenidyl-d 5 hydrochloride	-	>99.50%
GC84306	Trihexyphenidyl-d 5 hydrochloride is deuterium labeled Trihexyphenidyl hydrochloride.
GC84320	TRV045	2256030-24-5	>98.00%
GC84320	TRV045 is a selective Sphingosine-1-phosphate subtype 1 receptor agonist with no effect on lymphocyte transport.
GC84330	TUG-2181	2653994-24-0	>98.00%
GC84330	TUG-2181 is an antagonist of GPR84 with an IC 50 value of 34 nM.
GC84344	UKH-1114	2113664-14-3	>99.50%
GC84344	UKH-1114 is a selective TMEM97 (a sigma-2 receptor) agonist with a K i values of 1279 and 46 nM for σ1R and σ2R/ TMEM97, respectively.
GC84373	Vasorelaxant agent-2	53242-88-9	-
GC84373	Vasorelaxant agent-2 (Compound 8h) targets α1A-adrenergic receptor with an affinity of pD2=5.4.
GC84394	VU0467319	1432438-14-6	>98.50%
GC84394	VU0467319 (Compound VU319) is a highly selective and blood-brain-permeable, orally active M1 positive allosteric modulator (PAM) ( EC 50: 492 nM).
GC84395	VU6043653	3032791-06-0	>99.50%
GC84395	VU6043653 is a potent, selective and cross the blood-brain barrier metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC 50 value of 325 nM for h mGlu5 [1] .
GC84396	VVD-699	3055319-82-6	>99.50%
GC84396	VVD-699 is a covalent blocker of the RAS-p110α interaction with oral activity.
GC84417	Xanomeline-d 3	175615-28-8	>99.00%
GC84417	Xanomeline-d 3 (LY-246708-d 3 ) is deuterium labeled Xanomeline.
GC84432	YM-31636 free base	159081-22-8	>98.50%
GC84432	YM-31636 free base is an orally active, potent and selective 5-HT 3 receptor agonist with a K i value of 0.2 nM.
GC84433	YNT-185	1804978-81-1	>98.00%
GC84433	YNT-185 is a nonpeptide, selective orexin type-2 receptor (OX2R) agonist, with EC 50 s of 0.028 and 2.75 μM for OX2R and OX1R, respectively.
GC84435	YT 146	90596-75-1	>99.50%
GC84435	YT 146 is a potent agonist of A2 adenosine receptor (A2 AR) agonist.
GC84441	Z-3578	473687-20-6	>99.50%
GC84441	Z-3578 is an orally active small-molecule antagonist of MrgX2 with potent antipseudoallergic activity, exhibiting a K D value of 729 nM.
GC84447	ZCL279	664975-73-9	>99.00%
GC84447	ZCL279 is a small molecule modulator (SMM) that inhibits Cdc42-intersectin (ITSN) interaction.