GPCR/G protein

Peptide R (TFA) is a synthetic and specific CXCR4 antagonist.

Perelintide (ZP8396) acetate is a dual amyli n and calcitonin receptor agonist (DACRA).

Petrelintide (ZP8396) is a dual amylin and calcitonin receptor agonist (DACRA) Petrelintide elicits a selective reduction in high-fat diet intake in diet-induced obese (DIO) rats, which is accompanied by a loss of fat mass and preservation of lean mass during weight reduction.

PF-06835375 is a selective, humanized CXCR5 -targeting immunoglobulin G1 antibody.

Prednisone-d 7 (Dehydrocortisone-d 7 ) is deuterium labeled Prednisone.

Pregnenolone-d 4 is the deuterium labeled Pregnenolone.

Pregnenolone monosulfate-d 4 sodium is the deuterium labeled Pregnenolone monosulfate sodium.

Quin-C7 is an orally active FPR2/ALX antagonist.

(R,R)-Suntinorexton is a isomeride of Suntinorexton.

(R)-Viloxazine-d 5 hydrochloride ((R)-Viloxazin-d 5 hydrochloride; (R)-Emovit-d 5 hydrochloride) is the deuterated-labeled (R)-Viloxazine hydrochloride.

(R)-YNT-3708 is a selective orexin 1 (OX 1 R) agonist, with an EC 50 of 7.48 nM.

(R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant.

(Rac)-SCH 563705 is a racemic mixture of SCH 563705.

Remlifanserin (ACP-204) is a highly selective 5-HT2A inverse agonist.

Rezuforimod (AGN-232411; AG-80308) is an ophthalmic solution targeting the formyl peptide receptor (FPR) pathway.

RFRP-3 (mouse) is a functional ortholog of avian gonadotropin inhibitory hormone (GnIH), binding to GPR147.

RMC-5127 is a small molecule inhibitor that binds to GTP-targeted KRAS G12V, with oral bioavailability and blood-brain barrier permeability.

RVD-Hpα TFA is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.

Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual cannabinoid CB1 receptor and inducible NOS antagonist.

S)-Praziquantel is a inactive distomer of R-praziquantel [1] .

(S)-SCH 563705 is a S-enantiomer of SCH 563705.

(S)-VU0637120 is a Y4R antagonist that effectively reduces the binding response of its endogenous ligand, pancreatic polypeptide (PP), on Y4R, with an IC 50 value of 2.7 μM.

(S)-YNT-3708, the S-enantiomer of YNT-3708, with low activity for OX1R and OX2R (EC 50 = 3595 nM and 1661 nm, respectively) [1] .

Ecopipam (SCH 39166) hydrobromide is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with K i s of 1.2 nM and 2.0 nM, respectively.