Accueil>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>1-Methylnicotinamide (chloride)

1-Methylnicotinamide (chloride) (Synonyms: N1-Methylnicotinamide chloride, Nicotinamide methochloride, Trigonellamide chloride)

Catalog No.GC42000

Le 1-méthylnicotinamide (chlorure) (chlorure de 1-méthylnicotinamide) est un métabolite endogène.

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1-Methylnicotinamide (chloride) Chemical Structure

Cas No.: 1005-24-9

Taille Prix Stock Qté
100mg
33,00 $US
En stock
500mg
81,00 $US
En stock
1g
128,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Nicotinamide is a precursor of NAD and NADP , which serve essential functions in modulating cellular redox status and controlling signaling and transcriptional events. 1-Methylnicotinamide (MNA) is a primary metabolite of nicotinamide produced by the action of nicotinamide N-methyltransferase . It demonstrates antithrombotic and anti-inflammatory properties through direct action on the endothelium by a mechanism involving the prostacyclin pathway and by improving nitric oxide bioavailability. Aggressive cancer cell lines are reported to have higher levels of MNA due to increased NNMT-directed transfer of methyl groups from S-adenosyl-L-methionine to nicotinamide, implicating a role for MNA in cancer cell metabolism.

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