Angoline hydrochloride |
Catalog No.GC60586 |
Le chlorhydrate d'angoline est un inhibiteur puissant et sélectif de la voie de signalisation IL6/STAT3 avec une IC50 de 11,56 μM. Le chlorhydrate d'angoline inhibe la phosphorylation de STAT3 et l'expression de son gène cible, et inhibe la prolifération des cellules cancéreuses.
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Cas No.: 1071676-04-4
Sample solution is provided at 25 µL, 10mM.
Angoline hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor with an IC50 of 11.56 μM. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation[1].
[1]. Jiawei Liu, et al. Angoline: a selective IL-6/STAT3 signaling pathway inhibitor isolated from Zanthoxylum nitidum. Phytomedicine. Jul-Aug 2014;21(8-9):1088-91.
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