Accueil>>Lipids>> Sphingolipids>>C8 L-threo Ceramide (d18:1/8:0)

C8 L-threo Ceramide (d18:1/8:0) (Synonyms: L-threo Cer(d18:1/8:0), L-threo Ceramide (d18:1/8:0), N-octanoyl-L-threo-Sphingosine)

Catalog No.GC43111

C8 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.

Products are for research use only. Not for human use. We do not sell to patients.

C8 L-threo Ceramide (d18:1/8:0) Chemical Structure

Cas No.: 175892-44-1

Taille Prix Stock Qté
1mg
385,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

C8 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It is cytotoxic to U937 cells (IC50 = 10 μM) and, like C8 D-threo ceramide , induces nuclear DNA fragmentation 5- to 6-fold more potently than C8 L-erythro ceramide . C8 D-threo Ceramide also enhances V. cholerae cytolysin pore formation in liposome lipid membranes, as measured by calcein release, with a 50% release dose (RD50) value of ~30 μg/ml.

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Average Rating: 5 ★★★★★ (Based on Reviews and 22 reference(s) in Google Scholar.)

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