ER 819762 |
Catalog No.GC50722 |
ER 817692 est un antagoniste des récepteurs EP4 de la prostaglandine E2 (PGE2) hautement sélectif et actif par voie orale avec une CE50 de 70 nM contre le récepteur EP4 humain.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1155773-15-1
Sample solution is provided at 25 µL, 10mM.
Potent EP4 receptor antagonist (IC50 = 59 nM). Suppresses EP4-mediated Th1 differentiation, Th17 cell expansion, and IL-23 secretion by activated dendritic cells. Inhibits Th1 and Th17 cytokine production, suppresses collagen- and GPI-induced arthritis in mice. Attenuates CFA-induced inflammatory pain in rats. Analgesic. Orally bioavailable.
Average Rating: 5
(Based on Reviews and 36 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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