Evatanepag |
| Catalog No.GC19147 |
L'evatanepag (CP-533536) est un agoniste non prostanoÏde, puissant et sélectif des récepteurs EP2.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 223488-57-1
Sample solution is provided at 25 µL, 10mM.
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Evatanepag (CP-533536) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.IC50 value: 0.3 nM (EC50)Target PGE2in vitro: CP-533536 is a potent and selective EP2agonist. CP-533536 demonstrates the ability to heal fractures when administered locally as a single dose in rat models of fracture healing. CP-533536 demonstrates excellent in vitro potency against EP2 and selectivity against a broad panel of other targets.
References:
[1]. Cameron KO, et al. Discovery of CP-533536: an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation. Bioorg Med Chem Lett. 2009 Apr 1;19(7):2075-8.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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